Showing posts with label Obesity. Show all posts
Showing posts with label Obesity. Show all posts

Friday, January 17, 2020

Empowering the Women scientists in the field of Endocrinology: Obesity Middleeast 2020







The women in the Middle East, studying overseas has traditionally been made difficult or impossible by traditionally made differences with the west. This has prevented many women from benefiting from the academic rig-out and traditions of the best universities and exposure to the latest thinking and culture of intellectual exploration and challenge. A female contribution is must, as the research has shown the importance of women for economic growth.

Getting girls and women involved in STEM (Science, Technology, Engineering and Mathematics) is a big concern in Western countries. There are more and more efforts being driven by the community, schools and universities to encourage more representation of women in STEM, which has been lacking. In certain countries in the Middle East, things are the opposite. In fact, contrary to stereotypes and propaganda, women in STEM in Jordan, Qatar and the United Arab Emirates test better and feel more comfortable in mathematics than men, and are not intimidated to say they like science-based subjects.

Women’s now-a-days are overcoming these obstacles by launching their own start-ups from home, leveraging the internet and engaging through online platforms to reach new markets. In fact, one in three start-ups in the Arab World are founded or led by women, a higher percentage than in Silicon Valley.



Our 3rd Middle East Obesity, Bariatric Surgery and Endocrinology Congress  which is going to be held during April 27-28, 2020 at Dubai, UAE providing an opportunity for women’s in the field of Endocrinology to explore their ideas and research works the in the various fields like obesity, Bariatric surgery and women’s healthcare by enlightening their research work.

We wholeheartedly welcome the women researchers, scientists, and scholars from Universities/Industries having   long periods of research experience to join the gathering. We are happy to empower our women researcher's members through research award “The Women of Science Award” and give help to women scientists in vocation advancement and research direction through our joint efforts. Women Scientist can name meriting the honor through on the web. By granting prizes and partnerships in universal, territorial and national services, the Obesity and Endocrinology Congress underpins the profession of the most splendid women researchers.



Friday, February 15, 2019

Estrogen Hormone – In Diabetes Control ???





Estrogen is a hormone which is mainly associated with females. Men also produces Estrogen, but Higher levels of estrogen is produced by females. Although it is present in smaller amounts, yet it plays prominent role maintaining health.

Gender related differences is shown by Type 2 diabetes. It was found that There is reduced incidence of occurring of type 2 diabetes in premenopausal women.

Estrogen acts by improving insulin sensitivity and by suppressing Gluconeogenesis. Estrogen role in controlling glucose homeostasis had given profound of understand diabetes, obesity and interventions of potential diet.

Lowered Insulin resistance and plasma glucose levels have observed in clinical trails of estrogen Replacement therapy in postmenopausal women. This is because deficiency of estrogen or impaired estrogen signaling is found to be associated with fault in regulation of metabolic homeostasis and insulin resistance which results in the development of type 2 diabetes.

As we said premenopausal women are less prone to incidence of type 2 diabetes than with age -equivalent men, but after menopause this advantage in women will disappear with glucose homeostasis as a result of reduced estrogen levels in the body.

Estrogen with potential effect of reducing the occurring of type 2 diabetes causes risk of breast cancer or stroke as side effects of estrogen therapy. But development of targeted estrogens will mimic the therapeutic benefits without any side effects.

Estrogen reduces the risk of developing type 2 diabetes via transcription factor FOXO-1, which increases the insulin resistance and Suppresses Gluconeogenesis.

FOXO-1 plays important role in regulating glucose production via insulin signaling and it is a key component of insulin signaling pathway with regulates cellular growth, differentiation and metabolism.

Hepatic Glucose production is suppressed by Estrogen through activation of estrogen receptor signaling which is independent of receptor substrates Irs1 and Irs2 of insulin which had given a important mechanism for estrogen in regulation of glucose homeostasis.

By the development of novel selective ligands through direct target estrogen receptors prevent type 2 diabetes, cardiovascular disease and Obesity with rising abnormal sexual characteristics and breast cancer.

Fundamental understand of dietary interventions can play a crucial role in controlling weight gain, glucose levels and related harmful diseases.